Stanford Medicine researchers developed a computer algorithm called Peptide Predictor to identify potential hunger-related hormones produced by prohormone convertase 1/3. The team screened 373 prohormones and tested 100 peptides, including GLP-1, on lab mice and minipigs. They found a promising 12 amino acid-long peptide called BRP (BRINP2-related peptide) that reduced appetite in both animals by up to 50% and led to significant weight loss in obese mice over two weeks. Unlike Ozempic-like drugs, BRP's effects on the brain don't involve the GLP-1 receptor and don't cause GI symptoms or other side effects, suggesting it can be safely tolerated as a drug.
https://gizmodo.com/scientists-discover-potential-ozempic-rival-that-could-help-people-lose-weight-with-less-nausea-2000576324The US is bracing for a potentially violent evening as numerous significant tornadoes are expected to hit the central and southern states of Texas, Oklahoma, and Kansas, known as "Tornado Alley". The region's unique geography and weather conditions create volatile storm clouds that can spawn long-track and violent tornadoes. In 2024, at least 54 people lost their lives in US tornado-related incidents, according to NOAA data.
https://www.thenews.com.pk/latest/1292373-tornadoes-leave-at-least-33-dead-across-central-usA deadly tornado outbreak swept across the central US, claiming at least 33 lives since Friday. Another storm system is expected to hit the eastern US on Sunday, affecting millions of people from western New York to central Florida, with a slight risk of severe thunderstorms and hail storms.
https://news.bloomberglaw.com/insurance/washington-us-mid-atlantic-face-growing-risk-of-storms-sundayAt least 33 people were killed and dozens injured in tornadoes and violent storms that swept across the central US on Saturday. In Kansas, a severe dust storm caused a multi-vehicle crash that resulted in eight fatalities. The region is bracing for more tornadoes this weekend as forecasters warn of continued severe weather.
https://www.japantimes.co.jp/news/2025/03/16/world/central-us-tornadoes/At least 33 people were killed and dozens injured in tornadoes and violent storms that swept across the central US. In Kansas, eight people died in a multi-vehicle crash caused by low visibility during a severe dust storm. Missouri reported 12 fatalities and widespread damage, including destroyed marinas and downed trees and power lines. In Mississippi, six deaths were reported and three people were missing. Texas saw four deaths linked to vehicle accidents due to dust storms and fires, while Arkansas declared a state of emergency after three people died and 29 were injured. The National Weather Service warned of more tornadoes forecast for the central Gulf Coast states, including Mississippi and Tennessee.
https://www.ndtv.com/world-news/33-killed-as-tornadoes-rip-through-central-us-7933620At least 26 people have been killed in the US due to multiple tornadoes and dust storms that have caused widespread destruction across the country. The severe weather conditions were reported in several states, including Texas, Oklahoma, and Kansas.
https://www.firstpost.com/world/united-states/26-killed-as-multiple-tornadoes-dust-storms-wreak-havoc-across-the-us-13871740.htmlAt least 33 people were killed and dozens injured in a series of tornadoes and violent storms that hit the central United States, including Houston, on Saturday. The severe weather caused significant damage, with roofs torn off homes and large trucks overturned. Forecasters warned of more tornadoes to come this weekend.
https://www.manilatimes.net/2025/03/17/world/americas-emea/33-die-as-tornadoes-pummel-central-us/2073947The US Agency for Global Media (USAGM) will undergo significant changes following an executive order signed by President Donald Trump on March 14. The order aims to reduce non-statutory divisions within the agency, which funds independent international news organizations such as Radio Free Asia (RFA) and Voice of America (VOA).
https://laotiantimes.com/2025/03/16/white-house-cuts-funding-to-radio-free-asia-voice-of-america-other-global-media-outlets/Turkish President Recep Tayyip Murad has praised a draft law aimed at regulating migrant workers in the labor market, which includes measures to balance employer-employee relations. The law unifies medical references for work-related injuries and extends provisions to workers not covered by social security. It also reorganizes employment regulations for migrant workers and enhances protections for working women, including extended maternity leave and safeguards for sick leave.
https://www.jordantimes.com/news/local/senate-committee-approves-labour-law-amendments-boost-worker-protections