Brii Bio is developing a functional cure for HBV through multiple combination studies with its portfolio, including BRII-179, elebsiran, and tobevibart. Elebsiran, led by Brii Bio, is being evaluated in combination with PEG-IFNα, while tobevibart, also developed by Brii Bio, is being assessed in Phase 2 and 3 studies alongside elebsiran.
https://www.prnewswire.com/news-releases/brii-bio-unveils-new-data-from-its-ongoing-phase-2-ensure-study-at-apasl-2025-showcasing-brii-179s-unique-potential-to-prime-and-boost-higher-hbsag-loss-through-target-patient-identification-302415033.htmlEamon Dolan, a Vice President and Executive Editor at Simon & Schuster, has written "The Power of Parting" to dismantle the false idol of family by presenting familial estrangement as an empowering solution for those who need to escape trauma. Inspired by his own experience with grief, guilt, and shame after cutting ties with his mother, Dolan spent three years researching and interviewing other survivors to create a unique perspective on the subject. His book aims to highlight the prevalence of familial abuse, citing statistics such as 27% of the population affected, 81% of physical abuse committed by family members, and 90% of children living in countries where corporal punishment is still legal. Dolan hopes his work will help readers realize that survivors are heroes who have retained their humanity despite being raised in inhumane circumstances.
https://www.dailymail.co.uk/news/article-14511713/power-parting-eamon-dolan-mom-estrangement-book.htmlGary Prince, a 33-year-old father of three, locked himself in a Persimmon Homes show home in Yeovil, Somerset, after his family suffered seven years of severe mould and damp issues in their newbuild home. The stress has led to medical and mental health challenges for the entire family, with Mr. Prince's wife nearly divorcing him due to the unbearable living conditions. He took drastic action by moving into the show home, highlighting the contrast between the luxurious showroom and his own home's mould and fire safety issues. After a dramatic standoff, Persimmon Homes' managing director agreed to inspect the house, and Mr. Prince is now temporarily living in a single room with his family at a local hotel.
https://www.dailymail.co.uk/news/article-14539493/Father-three-locks-inside-developers-home.htmlReviva Pharmaceuticals Holdings, Inc., a pharmaceutical company developing treatments for schizophrenia, announced topline data from its Phase 3 RECOVER study on brilaroxazine, a potential therapy for stable schizophrenia patients. The results will be presented at the Schizophrenia International Research Society (SIRS) conference in Chicago, Illinois, where Dr. Laxminarayan Bhat, Reviva's CEO, will discuss the findings.
https://www.manilatimes.net/2025/03/30/tmt-newswire/globenewswire/reviva-to-present-brilaroxazine-topline-data-for-long-term-ole-portion-of-recover-study-in-schizophrenia-at-2025-sirs-congress/2082872A new virtual care kiosk has been set up at the Lawrence Allen Centre in Toronto to provide patients with access to medical consultations remotely. The kiosk, developed by SickKids and RioCan, offers high-speed Wi-Fi, a private room, and live interpreters who speak multiple languages. The initiative aims to address the "digital divide" and reach underserved communities, particularly those with limited technology access. The goal is to alleviate strain on emergency departments by providing an alternative for non-urgent care, allowing parents to attend virtual appointments without missing work or school, and reducing wait times of over 24 hours for reassurance and medication.
https://thestar.com/news/gta/inside-a-toronto-mall-a-new-kiosk-is-changing-how-families-access-health-care/article_9a8bff36-f0a8-4b9c-9dc3-324710462b6a.htmlBipolar disorder is a mental health condition characterized by extreme mood swings, including episodes of mania, hypomania, and depression. Individuals with bipolar disorder may experience feelings of euphoria, hallucinations, or psychosis, as well as reduced need for sleep and difficulty concentrating. The severity of symptoms can vary among individuals, but severe cases can significantly impact daily life, work, education, and social relationships. There are several types of bipolar disorder, including Bipolar I Disorder, characterized by mania, and Bipolar II Disorder, which involves major depressive episodes and hypomanic episodes. Symptoms can appear at any age, with diagnosis often occurring in adolescence or early twenties.
https://en.tempo.co/read/1992235/world-bipolar-day-march-30-detecting-bipolar-disorder-and-its-typesA study by the Avon Longitudinal Study of Parents and Children (ALSPAC) found that children who experience father absence during early childhood are more likely to develop depression in adolescence and early adulthood. The author, who struggled with mental health issues from a young age, was institutionalized at 8 years old after expressing suicidal thoughts due to the lack of a father figure in their life. This experience is part of what inspired them to write "The Children We Left Behind", highlighting the devastating impact of father absence on children's mental well-being and increasing the risk of suicide.
https://www.foxnews.com/opinion/children-we-left-behind-a-reckoning-with-americas-growing-fatherlessnessA doctor's practice often sees patients facing unrealistic expectations or requirements when trying to access medication for opioid addiction, leading to a cycle of stopping and restarting treatment. Despite recent federal efforts to ease prescription restrictions, treatment programs still need updates to align with the latest evidence. A certified recovery specialist at Penn Medicine's Center for Addiction Medicine and Policy in Philadelphia notes that effective programs can be identified through unofficial means, highlighting the need for more targeted support.
https://whyy.org/articles/opioid-addiction-medication-philadelphia-study-buprenorphine/Many professionals are reevaluating their career priorities, opting for positions with better work-life balance, reduced stress, and more job satisfaction over promotions. This shift is driven by individuals seeking to prioritize hobbies, family time, self-care, and personal fulfillment. As a result, people are choosing careers that align with their values, interests, and purpose, leading to improved mental and physical health, stronger relationships, and greater financial freedom. With the rise of remote work, entrepreneurship, and freelancing, individuals can now have more control over their schedules, allowing for increased job satisfaction and life enjoyment.
https://www.news18.com/lifestyle/health-and-fitness/career-glow-down-is-todays-workload-becoming-a-barrier-for-fulfilling-dreams-heres-why-people-choose-peace-over-promotion-9278648.html