Aquestive, a pharmaceutical company led by President and CEO Daniel Barber, is expecting to complete its process in the first quarter of 2025 and achieve FDA acceptance before the end of the second quarter of that year. This milestone will bring a non-device, non-invasive treatment option for severe allergic reactions, including anaphylaxis, closer to patients. Additionally, Aquestive's AQST-108 (epinephrine) Topical Gel is being advanced into Phase 2a clinical trial development for the treatment of alopecia areata.
https://markets.businessinsider.com/news/stocks/aquestive-therapeutics-reports-q4-eps-19c-consensus-13c-1034445478A decade-long collaboration between the Pediatric Praziquantel Consortium, led by Japan's Astellas Pharma Inc., has resulted in the development of arpraziquantel, a child-friendly treatment for schistosomiasis affecting 250 million people globally. The disease, also known as bilharzia, can lead to severe complications if left untreated and is particularly devastating among preschool-aged children. The GHIT Fund, a Japan-based international public-private partnership, has supported the development of arpraziquantel through its R&D portfolio, which aims to address neglected diseases in vulnerable populations. Arpraziquantel received European Medicines Agency approval in December 2023 and is expected to be included in the World Health Organization's Essential Medicines List in 2025.
https://www.prnewswire.com/news-releases/ghit-backed-innovation-achieves-landmark-new-treatment-option-for-schistosomiasis-reaches-preschool-aged-children-302391944.htmlAccording to nutritionist Sophie Bertrand, certain foods can help promote good sleep. Turkey is high in tryptophan, which increases melatonin production and helps regulate sleep. Almonds are a great source of magnesium and B vitamins, which have been shown to improve sleep duration and reduce nighttime awakenings. Bananas contain potassium and magnesium that help relax overstressed muscles and produce serotonin and melatonin, promoting relaxation and a healthy sleep-wake cycle. Tart cherry juice has high amounts of melatonin and has been studied for its role in relieving insomnia, increasing sleep time and quality. Mackerel is also a good dinner option as it contains omega-3 fatty acids that can help reduce restlessness and promote better sleep.
https://www.dailymail.co.uk/home/you/article-14459459/foods-stopping-you-sleeping-takeaway-juice-nutritionist.htmlA bombshell court filing in the case against Bryan Kohberger has revealed DNA evidence found under the fingernails of murder victim Madison Mogen, which was linked to Kohberger through Investigative Genetic Genealogy. The DNA analysis also found a "three person mixture" on Mogen's fingernail clippings, with the statistical likelihood that Kohberger is one of the individuals involved being redacted. Kohberger faces the death penalty if convicted at his trial in August and has requested that testimony about the DNA analysis be limited due to concerns it would violate his right to a fair trial.
https://www.dailymail.co.uk/news/article-14464651/idaho-murders-trial-dna-evidence-victim-fingernail-bryan-kohberger.htmlThe Consumer Financial Protection Bureau (CFPB) has dropped a lawsuit against several major banks, including JPMorgan Chase & Co., Bank of America Corp., and Wells Fargo & Co., as well as the parent company of Zelle, over allegations that they rushed out a peer-to-peer payment network that allowed fraud to spread.
https://news.bloomberglaw.com/litigation/cfpb-drops-lawsuit-against-us-banks-over-alleged-fraud-on-zelleAn Idaho judge has denied Bryan Kohberger's defense motion to suppress key evidence in the quadruple murder case. The decision was made despite claims by Kohberger's lawyer that police had an unfair advantage due to the presence of multiple officers at the crime scene, a point raised by Joseph Giacalone, a retired NYPD sergeant and cold case investigator. The murders took place in a six-bedroom house near the University of Idaho campus, where 20-year-old Xana Kernodle and her boyfriend Ethan Chapin, also 20, were found dead on an upper floor, alongside Kaylee Goncalves, 21, and her friend Madison Mogen, who was a marketing major from Coeur d'Alene.
https://www.foxnews.com/us/idaho-police-recovered-3-person-mixture-dna-under-maddie-mogen-fingernailsThe Internal Revenue Service (IRS) is planning to cut its workforce by up to half through layoffs and buyouts as part of a broader effort by Elon Musk's Department of Government Efficiency under the Trump administration to reduce the federal workforce. The IRS employs around 90,000 workers across the US, but former commissioner John Koskinen warns that such a reduction would render the agency "dysfunctional".
https://krcgtv.com/news/nation-world/irs-faces-potential-workforce-cut-by-half-under-musks-plan-for-government-efficiency-department-of-government-efficiency-doge-elon-president-donald-trump-internal-revenue-service-secretary-scott-bessent-kristi-noem#Jalan Journey, a startup co-founded by Sricharan Balasubramanian and Harrison Chong, has expanded its outreach to Malaysia, Vietnam, and Indonesia. The company aims to deliver an authentic experience for students through games that tackle themes such as disability inclusion, financial literacy, homelessness, environment, sustainability, and mental health. By engaging with stakeholders, including wheelchair users and schools, the team identifies gaps in existing programs and fills them with their games. Jalan Journey works closely with partners in schools and consults advisers from social service and education sectors to develop its content.
https://www.businesstimes.com.sg/startups-tech/startups/edtech-startup-jalan-journey-teaches-students-about-social-issues-through-digital-gamesLabour MP Josh MacAlister has proposed legislation to protect under-16s from addictive social media content on platforms like TikTok and Snapchat, but the plans have been met with opposition from Digital Secretary Peter Kyle and Education Secretary Bridget Phillipson. Instead of implementing tough controls, the Bill suggests that chief medical officers provide advice for parents on their children's smartphone use and calls for research into the impact of social media on children. The proposal has been put forward as a first step towards addressing the issue of excessive smartphone and social media use among young people, with 74% of people in a recent poll supporting a ban on under-16s using social media.
https://www.dailymail.co.uk/news/article-14465425/Bid-stop-children-doom-scrolling-social-media-apps-TikTok-Snapchat-watered-Labour-ministers-oppose-tough-crackdown.html